Can a personal assistant be self employed rather than being an employee?

Personal assistants, under HMRC
rules, usually work under an employed
arrangement.
Skills for Care’s ‘Understanding the
employment status of personal assistants’
guide may be helpful, and you can
download it at: www.skillsforcare.org.uk/
PAemploymentstatus.
You can also check any employment
arrangement directly with HMRC, by using
their ‘Check employment status for tax’
tool at: www.gov.uk/guidance/check-employment-status-for-tax